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A Brief History of Takeda Pharmaceuticals

Takeda Pharmaceuticals and Actos®

Takeda Pharmaceuticals has a long, rich history that goes back hundreds of years but its history of lawsuits is happening right now. All in all, this is why Daviagra overnight dangerous products medical attorneys legal firms and lawyers have been active as of late with various complaints concerning Depakote, Actos, Plavix, Topamax and the like. Takeda was originally founded in Osaka, Japan in 1781. Though it wasn’t known as Takeda Pharmaceuticals then, it was just a single medicine shop. It began importing Western medicine in 1871 and built its first manufacturing facility in 1895. Back then, it was known as Chobei Takeda & Company Limited, and by 1925 it held a net worth of about one million dollars.

Following World War II, Takeda’s primary products included penicillin and B1 vitamin. It became a publicly traded company by 1949 and, until 1970, grew as much as 20% each year. In 1985, Takeda released a new cancer-fighting drug, Lupron, in the United States. With Lupron Depot (a successor of Lupron) and Prevacid, Takeda found itself expanding into both American and European markets. Needless to say, various Dangerous products medical attorneys and related law firms have ben busy with these civil court cases and proceedings.

Takeda Pharmaceuticals began to turn its focus to Actos® in 1999. Just two years later, Actos® alone was earning Takeda Pharmaceuticals nearly half of the company’s yearly net sales. But the focus soon began to shift as new research into Actos® showed an increased risk of serious, life-changing side effects, particularly for patients who took Actos® for long periods of time. The most common of the side effects linked to Actos® are an increased risk of bladder cancer and also congestive heart failure.

More Information Regarding Side Effects

Patients soon began coming forward who were suffering from these long-term side effects. Many began filing lawsuits against Takeda as well as again Eli Lilly, the company that helped Takeda market the drug in the United States.

Actos® sales since 1999 suggest that over 10 million people around the world have take the drug. Given the risks of side effects when taking Actos®, this would mean that as many as thousands of people worldwide could be suffering or could soon be suffering from the dangerous side effects of Actos®.

Further studies showed an increasing risk of other side effects for patients taking Actos®. A 2001 study displayed a 40% increased risk of bladder cancer in patients who took Actos® for more than a year. Actos® has also been linked to an eye disorder called macular edema and an increased risk of bone fracture in women.

After further research in 2007 showed that Actos® and similar drugs, such as Avandia, increased the risk of congestive heart failure in patients taking the drug, the U.S. Food and Drug Administration (FDA) added a black-box warning label. Though Avandia’s sales declined, Actos® became more popular. Despite a growing mountain of evidence against it, Actos® remains available within the United States.

Other Drugs Manufactured by Takeda

Takeda had planned to replace Actos® after its patent expired in August 2012 with another new diabetes drug, Alogliptin. The FDA rejected Alogliptin, however, due to insufficient data on the drug’s heart risks.

At the moment, clinical trials are underway for Takeda’s new weight loss drug in addition to a new class of diabetes drugs called TAK-875. This is where a Dangerous Medical Products attorney legal firm is needed.

 

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