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A Brief History of Takeda Pharmaceuticals

Takeda Pharmaceuticals and Actos®

Takeda Pharmaceuticals has a long, rich history that goes back hundreds of years but its history of lawsuits is happening right now. All in all, this is why Daviagra overnight dangerous products medical attorneys legal firms and lawyers have been active as of late with various complaints concerning Depakote, Actos, Plavix, Topamax and the like. Takeda was originally founded in Osaka, Japan in 1781. Though it wasn’t known as Takeda Pharmaceuticals then, it was just a single medicine shop. It began importing Western medicine in 1871 and built its first manufacturing facility in 1895. Back then, it was known as Chobei Takeda & Company Limited, and by 1925 it held a net worth of about one million dollars.

Following World War II, Takeda’s primary products included penicillin and B1 vitamin. It became a publicly traded company by 1949 and, until 1970, grew as much as 20% each year. In 1985, Takeda released a new cancer-fighting drug, Lupron, in the United States. With Lupron Depot (a successor of Lupron) and Prevacid, Takeda found itself expanding into both American and European markets. Needless to say, various Dangerous products medical attorneys and related law firms have ben busy with these civil court cases and proceedings.

Takeda Pharmaceuticals began to turn its focus to Actos® in 1999. Just two years later, Actos® alone was earning Takeda Pharmaceuticals nearly half of the company’s yearly net sales. But the focus soon began to shift as new research into Actos® showed an increased risk of serious, life-changing side effects, particularly for patients who took Actos® for long periods of time. The most common of the side effects linked to Actos® are an increased risk of bladder cancer and also congestive heart failure.

More Information Regarding Side Effects

Patients soon began coming forward who were suffering from these long-term side effects. Many began filing lawsuits against Takeda as well as again Eli Lilly, the company that helped Takeda market the drug in the United States.

Actos® sales since 1999 suggest that over 10 million people around the world have take the drug. Given the risks of side effects when taking Actos®, this would mean that as many as thousands of people worldwide could be suffering or could soon be suffering from the dangerous side effects of Actos®.

Further studies showed an increasing risk of other side effects for patients taking Actos®. A 2001 study displayed a 40% increased risk of bladder cancer in patients who took Actos® for more than a year. Actos® has also been linked to an eye disorder called macular edema and an increased risk of bone fracture in women.

After further research in 2007 showed that Actos® and similar drugs, such as Avandia, increased the risk of congestive heart failure in patients taking the drug, the U.S. Food and Drug Administration (FDA) added a black-box warning label. Though Avandia’s sales declined, Actos® became more popular. Despite a growing mountain of evidence against it, Actos® remains available within the United States.

Other Drugs Manufactured by Takeda

Takeda had planned to replace Actos® after its patent expired in August 2012 with another new diabetes drug, Alogliptin. The FDA rejected Alogliptin, however, due to insufficient data on the drug’s heart risks.

At the moment, clinical trials are underway for Takeda’s new weight loss drug in addition to a new class of diabetes drugs called TAK-875. This is where a Dangerous Medical Products attorney legal firm is needed.


Can I make payments on DUI fines in Arizona?

When you are convicted of DUI in Arizona or any other criminal charges, it is critical that you pay the court fines and fees on time. By not paying these or meeting the requirements of any payment arrangements, you can be required to serve jail time and may suffer even greater expense due to interest charges and other added fees. If you are facing charges, it is important to enlist the help of an experienced Arizona DUI criminal defense attorney. Such an attorney can help you throughout your case, even possibly helping you to gain lesser charges or reduced sentencing and fines.

Payment Options Do Exist for Defendants in Arizona

Arizona DUI defendants ordered to pay fines or fees can receive an option from the courts to pay the fees in (more…)

Does having a DUI affect getting hired?

Convicted of a Crime on Job Application


Finding a job in today’s economy can be tough. Although that is a difficult task on its own for the best of candidates, adding an Arizona DUI conviction to your record can make a job search even more problematic. At best, you may find yourself embarrassed about your poor decision-making that led to DUI charges. At worst, you may not be able to work in your chosen field, travel to other countries without extra hassles or maintain the trust of your peers when you do gain a position. Even just getting to work each day can be made difficult, if you have a suspended or revoked driver’s license.

If you are charged with DUI in Arizona, it is very important that you seek the advice of a licensed Arizona DUI defense attorney. Through the help of an experienced lawyer, you can fight the charges for a possible dismissal or reduction of those charges or reduced sentencing. (more…)

How to Remove a DUI off My Record

When you are arrested or convicted of drunk driving, resulting criminal charges can heavily affect your daily life. You may lose your job, struggle to find a new position, get expelled from college and even suffer credit problems. Your insurance is likely to cost more. Also, if you are in politics or hold other positions scrutinized by the public, you will likely experience trouble gaining those roles in the future – if you are eligible to hold office, at all.

In Arizona, if you have been convicted of DUI you may be eligible for a Set Aside. A Set Aside is similar to expungement of criminal records in other states. To find out if a Set Aside will work to clear DUI conviction from your criminal record, call the Law Offices of David M. Cantor.

What a Set Aside / Expungement can do for DUI Convictions

Depending upon the circumstances of each individual’s case, it is often possible to have a DUI, drug-related or other conviction removed from your public record by a lawyer for expungement or Set Aside. First, you must complete all of the conditions of your sentence and associated probation. If you have achieved this and have otherwise cooperated as you should, the court may agree to have your DUI or criminal records Set Aside. This means that the conviction will be cleaned from your record, as if you were never found guilty. (more…)

False DUI Breathalyzer Results from Foreign Substances

When you are suspected of DUI and administered a breathalyzer test, there are a multitude of substances that can affect your test results. Even if you have not been drinking alcohol, you can still be arrested if your breathalyzer test registers over the national legal limit of 0.08 percent for blood alcohol content (BAC).

When a proper defense is needed for your breathalyzer test results as part of a DUI case, it is important to get the help of a lawyer as soon as possible. Your criminal defense attorney can help you build a strong, aggressive defense against these charges.

What Causes Breathalyzers to Register Positive for BAC?

When you have not been drinking, but have a positive result for BAC during a breathalyzer test, there are several things that may have caused this “false positive.” These include asthma inhalants, administered by patients directly through a device much like a breathalyzer, called an inhaler. (more…)

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